Projects

WORK STREAM

PROJECT DESCRIPTION

COORDINATOR

PARTNERS

STATUS

EVIDENCE-BASED PATHOLOGY

The Evidence-Based Pathology Training Initiative (Evi-Pat)

Uta Schmidt-Strassburger

IARC, Ulm University

Closed

BBEST: The Blue Books Expert Selection App

Ramon Cierco, Ian Cree

IARC, Universitat Autònoma de Barcelona

Closed

Mapping the Evidence for the WHO Classification of Tumours: A Living Evidence Gap Map by Tumour Type (WCT-EVI-MAP)

Dilani Lokuhetty, IARC Systematic Reviewer

IARC, DHM German Heart Centre Munich, ISCIII Instituto de Salud Carlos III, Nuffield Department of Surgical Sciences - University of Oxford, Newcastle University, Maria Sklodowska-Curie National Research Institute of Oncology, Singapore Breast Surgery Centre - Luma

Ongoing

Refining the classification of breast phyllodes tumours (PTs)

Puay Hoon Tan

Singapore Breast Surgery Center - Luma

Ongoing

The clinical utility of whole genome, transcriptome, and methylation sequencing and proteomics in classifying “unclassifiable” tumours

Stephen Fox

Peter MacCallum Cancer Centre

Ongoing

QUALITY IN RESEARCH

Developing ISO standards for research laboratories

Zisis Kozlakidis

IARC, ISO

Ongoing

In planning: External quality assessment (EQA) for molecular pathology

Francesca Fenizia

IQN Path

TBD

INTERNATIONAL DATABASE
COORDINATION

In planning: Coordination of databases on rare tumours

Rita Alaggio

Ospedale Bambino Gesù

TBD

In planning: Very rare childhood sarcomas

Rita Alaggio

Ospedale Bambino Gesù, Centre Léon Bérard

Approved

COMPUTATIONAL PATHOLOGY

Autopsy Reporting System

Ian Cree

IARC, all IC3R partners

Closed

In planning: Whole slide image use and quality, best practices

Ian Cree

TBD

TBD

In planning: SARCOMICS-AI: Understanding the morphological features underlying phenotypic convergence to undifferentiated state in soft-tissue sarcomas and related tumours

Matthieu Foll

Rare Cancers Genomics initiative

Approved

Pathologist Annotation Datasets for Evaluating Algorithms (PADEA)

Brandon Gallas

Office of Science and Engineering Laboratories (OSEL), United States Food and Drug Administration (FDA)

Ongoing

A WHO Pilot Project for Global Digital Consultation Based on Blue Book Cancer Atlases: Designing, Developing, and Validating an AI-Driven Image Search Engine for Breast Cancer Subtypes to Provide Computational Second Opinions through Biopsy Matching

Hamid Tizhoosh

KIMIA Lab - University of Waterloo, University of British Columbia, University Health Network, BC Cancer, Provincial Health Services Authority, IARC

Closed

MOLECULAR
PATHOLOGY
AND GENETICS

In planning: classNET: reconciling lung carcinoid histopathological and molecular classifications with AI

Matthieu Foll

Rare Cancers Genomics initiative

Approved

In planning: Identifying molecular markers for the diagnosis of malignant pleural mesothelioma (MPM) archetypes

Lynnette Fernandez-Cuesta

Rare Cancers Genomics initiative

Approved

In planning: Identifying molecular markers for the diagnosis of lung “supra-carcinoids” and the other lung neuroendocrine tumours (NET) molecular groups

Lynnette Fernandez-Cuesta

Rare Cancers Genomics initiative

Approved

In planning: Early cancer detection in patients with genetic tumour syndromes (ECD-GTS)

Ian Cree

IARC

Approved

In planning: Molecular classification of tumours (Mol-WCT)

Ian Cree

IARC

Approved

In planning: Liquid Biopsies

Stefan Holdenrieder

DHM German Heart Centre Munich, IQN Path, IARC

Approved

For any questions related to projects, please contact us at ic3r@iarc.who.int.