IC3R: Projects

WORK STREAM	PROJECT DESCRIPTION	COORDINATOR	PARTNERS	STATUS
EVIDENCE-BASED PATHOLOGY	The Evidence-Based Pathology Training Initiative (Evi-Pat)	Uta Schmidt-Strassburger	IARC, Ulm University	Closed
	BBEST: The Blue Books Expert Selection App	Ramon Cierco, Ian Cree	IARC, Universitat Autònoma de Barcelona	Closed
	Mapping the Evidence for the WHO Classification of Tumours: A Living Evidence Gap Map by Tumour Type (WCT-EVI-MAP)	Dilani Lokuhetty, Iciar Indave	IARC, TUM German Heart Center, ISCIII Instituto de Salud Carlos III, Nuffield Department of Surgical Sciences - University of Oxford, Newcastle University, Maria Sklodowska-Curie National Research Institute of Oncology, Singapore Breast Surgery Centre - Luma	Ongoing
	Refining the classification of breast phyllodes tumours (PTs)	Puay Hoon Tan	Singapore Breast Surgery Center - Luma	Ongoing
	The clinical utility of whole genome, transcriptome, and methylation sequencing and proteomics in classifying “unclassifiable” tumours	Stephen Fox	Peter MacCallum Cancer Centre	Ongoing
QUALITY IN RESEARCH	Developing ISO standards for research laboratories	Zisis Kozlakidis	IARC, ISO	Ongoing
QUALITY IN RESEARCH	In planning: External quality assessment (EQA) for molecular pathology	Francesca Fenizia	IQN Path	TBD
INTERNATIONAL DATABASE COORDINATION	In planning: Coordination of databases on rare tumours	Rita Alaggio	Ospedale Bambino Gesù	TBD
INTERNATIONAL DATABASE COORDINATION	In planning: Very rare childhood sarcomas	Rita Alaggio	Ospedale Bambino Gesù, Centre Léon Bérard	Approved
COMPUTATIONAL PATHOLOGY	Autopsy Reporting System	Ian Cree	IARC, all IC³R partners	Closed
	In planning: Whole slide image use and quality, best practices	Ian Cree	TBD	TBD
	In planning: SARCOMICS-AI: Understanding the morphological features underlying phenotypic convergence to undifferentiated state in soft-tissue sarcomas and related tumours	Matthieu Foll	Rare Cancers Genomics initiative	Approved
	Pathologist Annotation Datasets for Evaluating Algorithms (PADEA)	Brandon Gallas	Office of Science and Engineering Laboratories (OSEL), United States Food and Drug Administration (FDA)	Closed
	A WHO Pilot Project for Global Digital Consultation Based on Blue Book Cancer Atlases: Designing, Developing, and Validating an AI-Driven Image Search Engine for Breast Cancer Subtypes to Provide Computational Second Opinions through Biopsy Matching	Hamid Tizhoosh	KIMIA Lab - University of Waterloo, University of British Columbia, University Health Network, BC Cancer, Provincial Health Services Authority, IARC	Closed
MOLECULAR PATHOLOGY AND GENETICS	In planning: classNET: reconciling lung carcinoid histopathological and molecular classifications with AI	Matthieu Foll	Rare Cancers Genomics initiative	Approved
	In planning: Identifying molecular markers for the diagnosis of malignant pleural mesothelioma (MPM) archetypes	Lynnette Fernandez-Cuesta	Rare Cancers Genomics initiative	Approved
	In planning: Identifying molecular markers for the diagnosis of lung “supra-carcinoids” and the other lung neuroendocrine tumours (NET) molecular groups	Lynnette Fernandez-Cuesta	Rare Cancers Genomics initiative	Approved
	In planning: Advancing Early Detection of Heritable Cancers in European Regions: Surveillance for Cancer in Genetic Tumour Syndromes (SCAN-GTS)	Ian Cree, Iciar Indave	IARC	Approved
	In planning: Molecular classification: supplementing the WCT (Mol-WCT)	Ian Cree	IARC	Approved
	In planning: Liquid Biopsies	Stefan Holdenrieder, Francesca Fenizia	TUM German Heart Center, IQN Path, IARC	Approved

For any questions related to projects, please contact us at ic3r@iarc.who.int.